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Treatment response to osimertinib in a patient with leptomeningeal metastasis from lung adenocarcinoma following failure of gefitinib and erlotinib: A case report

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are effective in the treatment of advanced non-small-cell lung cancer (NSCLC) with leptomeningeal metastases (LM); however, a proportion of the patients with resistant tumors do not benefit from EGFR-TKI treatment. In the presen...

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Bibliographic Details
Published in:Mol Clin Oncol
Main Authors: Li, Junjun, Liu, Xiaomei, Yuan, Caijun
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090575/
https://ncbi.nlm.nih.gov/pubmed/30112177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2018.1666
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