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Analysis of FK506-mediated functional recovery and neuroprotection in a rat model of spinal cord injury indicates that EGF is modulated in astrocytes

The present study aimed to evaluate whether the application of tacrolimus (FK506) could improve functional recovery in spinal cord injury (SCI) rat models by activating astrocytes, and to further investigate the underlying mechanisms of this action. Male Sprague-Dawley rats (n=56) were used to estab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Cai, Jun, Sun, Yu, Yin, Zaoyang, Wang, Daode, Shi, Kun, Fu, Yuxuan, Cao, Xiaojian, Ge, Yingbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090233/
https://ncbi.nlm.nih.gov/pubmed/30116308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6283
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