Analysis of FK506-mediated functional recovery and neuroprotection in a rat model of spinal cord injury indicates that EGF is modulated in astrocytes

The present study aimed to evaluate whether the application of tacrolimus (FK506) could improve functional recovery in spinal cord injury (SCI) rat models by activating astrocytes, and to further investigate the underlying mechanisms of this action. Male Sprague-Dawley rats (n=56) were used to estab...

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Bibliographic Details
Published in:Exp Ther Med
Main Authors: Cai, Jun, Sun, Yu, Yin, Zaoyang, Wang, Daode, Shi, Kun, Fu, Yuxuan, Cao, Xiaojian, Ge, Yingbin
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090233/
https://ncbi.nlm.nih.gov/pubmed/30116308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6283
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