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Nobiletin protects PC12 cells from ERS-induced apoptosis in OGD/R injury via activation of the PI3K/AKT pathway

Nobiletin (NOB) possesses multiple pharmacological effects, but its anti-apoptotic property has acquired a great deal of attention. Endoplasmic reticulum (ER) stress (ERS)-induced apoptosis acts as the pivotal aetiology in neuronal oxygen-glucose deprivation and reoxygenation (OGD/R) injury. The aim...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Li, Zi-Ru, Yang, Lei, Zhen, Jin, Zhao, Yan, Lu, Zu-Neng
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090223/
https://ncbi.nlm.nih.gov/pubmed/30116396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6330
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