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Endogenous HIF2A reporter systems for high-throughput functional screening

Tissue-specific transcriptional programs control most biological phenotypes, including disease states such as cancer. However, the molecular details underlying transcriptional specificity is largely unknown, hindering the development of therapeutic approaches. Here, we describe novel experimental re...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Zaini, M. Nazhif, Patel, Saroor A., Syafruddin, Saiful E., Rodrigues, Paulo, Vanharanta, Sakari
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089976/
https://ncbi.nlm.nih.gov/pubmed/30104738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30499-2
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