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Endogenous HIF2A reporter systems for high-throughput functional screening

Tissue-specific transcriptional programs control most biological phenotypes, including disease states such as cancer. However, the molecular details underlying transcriptional specificity is largely unknown, hindering the development of therapeutic approaches. Here, we describe novel experimental re...

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Опубликовано в: :Sci Rep
Главные авторы: Zaini, M. Nazhif, Patel, Saroor A., Syafruddin, Saiful E., Rodrigues, Paulo, Vanharanta, Sakari
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089976/
https://ncbi.nlm.nih.gov/pubmed/30104738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30499-2
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