Drug-based perturbation screen uncovers synergistic drug combinations in Burkitt lymphoma

Burkitt lymphoma (BL) is a highly aggressive B-cell lymphoma associated with MYC translocation. Here, we describe drug response profiling of 42 blood cancer cell lines including 17 BL to 32 drugs targeting key cancer pathways and provide a systematic study of drug combinations in BL cell lines. Base...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tomska, K., Kurilov, R., Lee, K. S., Hüllein, J., Lukas, M., Sellner, L., Walther, T., Wagner, L., Oleś, M., Brors, B., Huber, W., Zenz, T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089937/
https://ncbi.nlm.nih.gov/pubmed/30104685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30509-3
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