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The pharmacokinetics, pharmacodynamics and tolerability of PUR0200, a novel tiotropium formulation, in chronic obstructive pulmonary disease

AIMS: PUR0200 is a tiotropium bromide formulation engineered with the iSPERSE dry powder delivery technology. PUR0200 is being developed as a bioequivalent alternative to tiotropium bromide, delivered using Spiriva® HandiHaler® (HH). We investigated the bronchodilator effects, pharmacokinetics and s...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Singh, Dave, Ravi, Arjun, Kane, Katie, Schmalbach, Tess, Hava, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089803/
https://ncbi.nlm.nih.gov/pubmed/29790581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13645
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