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Hypoxia-induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF-1α
The placenta initially develops in a low-oxygen environment up to week 8–10 of gestation, and a low oxygen level is a critical factor in the regulation of trophoblast migration and invasion. CXC chemokine receptor 4 (CXCR4) is transcriptionally activated by hypoxia in cancer cells. However, whether...
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| Publicado no: | Int J Mol Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089771/ https://ncbi.nlm.nih.gov/pubmed/29786753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3701 |
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