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Impaired transmissibility of atypical prions from genetic CJD(G114V)
OBJECTIVE: To describe the clinicopathologic, molecular, and transmissible characteristics of genetic prion disease in a young man carrying the PRNP-G114V variant. METHODS: We performed genetic, histologic, and molecular studies, combined with in vivo transmission studies and in vitro replication st...
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| Pubblicato in: | Neurol Genet |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wolters Kluwer
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089695/ https://ncbi.nlm.nih.gov/pubmed/30109268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000253 |
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