Patient derived renal cell carcinoma xenografts exhibit distinct sensitivity patterns in response to antiangiogenic therapy and constitute a suitable tool for biomarker development

Systemic treatment is necessary for one third of patients with renal cell carcinoma. No valid biomarker is currently available to tailor personalized therapy. In this study we established a representative panel of patient derived xenograft (PDX) mouse models from patients with renal cell carcinomas...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Schueler, Julia, Klingner, Kerstin, Bug, Daniel, Zoeller, Caren, Maier, Armin, Dong, Meng, Willecke, Kerstin, Peille, Anne-Lise, Steiner, Eva, Landesfeind, Manuel, Copland, John A., Siegers, Gabrielle M., Haferkamp, Axel, Boehm, Katharina, Tsaur, Igor, Schneider, Meike
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089561/
https://ncbi.nlm.nih.gov/pubmed/30123419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25697
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