Patient derived renal cell carcinoma xenografts exhibit distinct sensitivity patterns in response to antiangiogenic therapy and constitute a suitable tool for biomarker development

Systemic treatment is necessary for one third of patients with renal cell carcinoma. No valid biomarker is currently available to tailor personalized therapy. In this study we established a representative panel of patient derived xenograft (PDX) mouse models from patients with renal cell carcinomas...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Schueler, Julia, Klingner, Kerstin, Bug, Daniel, Zoeller, Caren, Maier, Armin, Dong, Meng, Willecke, Kerstin, Peille, Anne-Lise, Steiner, Eva, Landesfeind, Manuel, Copland, John A., Siegers, Gabrielle M., Haferkamp, Axel, Boehm, Katharina, Tsaur, Igor, Schneider, Meike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089561/
https://ncbi.nlm.nih.gov/pubmed/30123419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25697
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi