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Resolution and uniqueness of estimated parameters of a model of thin filament regulation in solution

The estimation of chemical kinetic rate constants for any non-trivial model is complex due to the nonlinear effects of second order chemical reactions. We developed an algorithm to accomplish this goal based on the Damped Least Squares (DLS) inversion method and then tested the effectiveness of this...

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Detalhes bibliográficos
Publicado no:Comput Biol Chem
Main Authors: Mijailovich, Srboljub M., Li, Xiaochuan, del Álamo, Juan C., Griffiths, R. Hugh, Kecman, Vojislav, Geeves, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089521/
https://ncbi.nlm.nih.gov/pubmed/20060364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2009.11.002
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