Cooperative [Ca(2+)]-Dependent Regulation of the Rate of Myosin Binding to Actin: Solution Data and the Tropomyosin Chain Model

The regulation of muscle contraction by calcium involves interactions among actin filaments, myosin-S1, tropomyosin (Tm), and troponin (Tn). We have extended our previous model in which the TmTn regulatory units are treated as a continuous flexible chain, and applied it to transient kinetic data. We...

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Hlavní autoři: Geeves, Michael, Griffiths, Hugh, Mijailovich, Srboljub, Smith, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
Muscle, Motility, and Motor Protein
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117182/
https://ncbi.nlm.nih.gov/pubmed/21641313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.020
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