Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma

In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in chemo-resistance using primary human pancreatic cancer-derived cells (PCC) and Cancer Associated Fibroblasts (CAF). Autophagy flux, as measured by L...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Molejon, María Inés, Swayden, Mirna, Fanale, Daniele, Bintz, Jennifer, Gayet, Odile, Soubeyran, Philippe, Iovanna, Juan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089401/
https://ncbi.nlm.nih.gov/pubmed/30112111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25745
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