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Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma

In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in chemo-resistance using primary human pancreatic cancer-derived cells (PCC) and Cancer Associated Fibroblasts (CAF). Autophagy flux, as measured by L...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Molejon, María Inés, Swayden, Mirna, Fanale, Daniele, Bintz, Jennifer, Gayet, Odile, Soubeyran, Philippe, Iovanna, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089401/
https://ncbi.nlm.nih.gov/pubmed/30112111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25745
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