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CaMKII Metaplasticity Drives Aβ Oligomer-Mediated Synaptotoxicity
Alzheimer’s disease (AD) is emerging as a synaptopathology driven by metaplasticity. Indeed, reminiscent of metaplasticity, oligomeric forms of the amyloid-β peptide (oAβ) prevent induction of long-term potentiation (LTP) via the prior activation of GluN2B-containing NMDA receptors (NMDARs). However...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089247/ https://ncbi.nlm.nih.gov/pubmed/29898386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.036 |
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