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Tethered Particle Motion: an easy technique for probing DNA topology and transcription factor interactions

Tethered Particle Motion (TPM) is a versatile in vitro technique for monitoring the conformations a linear macro-molecule, such as DNA, can exhibit. The technique involves monitoring the diffusive motion of a tracker particle anchored to a fixed point via the macro-molecule of interest, which acts a...

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Vydáno v:Methods Mol Biol
Hlavní autoři: Kovari, Daniel T., Yan, Yan, Finzi, Laura, Dunlap, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089228/
https://ncbi.nlm.nih.gov/pubmed/28940077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7271-5_17
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