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Proteins mediating DNA loops effectively block transcription

Loops are ubiquitous topological elements formed when proteins simultaneously bind to two noncontiguous DNA sites. While a loop‐mediating protein may regulate initiation at a promoter, the presence of the protein at the other site may be an obstacle for RNA polymerases (RNAP) transcribing a differen...

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Publicat a:Protein Sci
Autors principals: Vörös, Zsuzsanna, Yan, Yan, Kovari, Daniel T., Finzi, Laura, Dunlap, David
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477534/
https://ncbi.nlm.nih.gov/pubmed/28295806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3156
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