Nalaganje...
Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer
Elevated expression of HER3, which interacts with HER2 in breast cancer cells, confers chemoresistance via phosphoinositide 3-kinase (PI-3K)/Akt-dependent upregulation of Survivin. However, the underlying mechanism is not clear. Ectopic expression or specific knockdown of HER3 in HER2-overexpressing...
Shranjeno v:
| izdano v: | Cancer Lett |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089084/ https://ncbi.nlm.nih.gov/pubmed/29409974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.01.065 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|