Chargement en cours...

Instability of TCF4 Triplet Repeat Expansion With Parent–Child Transmission in Fuchs' Endothelial Corneal Dystrophy

PURPOSE: Fuchs' endothelial corneal dystrophy (FECD) caused by the CTG triplet repeat expansion in the TCF4 gene (CTG18.1 locus) is the most common repeat expansion disorder. Intergenerational instability of expanded repeats and clinical anticipation are hallmarks of other repeat expansion diso...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Saade, Joanna S., Xing, Chao, Gong, Xin, Zhou, Zhengyang, Mootha, V. Vinod
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088802/
https://ncbi.nlm.nih.gov/pubmed/30098193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24119
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!