S100A4(+) Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts

S100A4, a calcium-binding protein, can promote pulmonary fibrosis via fibroblast activation. Due partly to its various cellular origins, the exact role of S100A4 in the development of lung fibrosis remains elusive. Here, we show that in the bronchoalveolar lavage fluid, numbers of S100A4(+) macropha...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Li, Yanan, Bao, Jing, Bian, Yangyang, Erben, Ulrike, Wang, Peigang, Song, Kun, Liu, Shuangqing, Li, Zhenzhen, Gao, Zhancheng, Qin, Zhihai
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088238/
https://ncbi.nlm.nih.gov/pubmed/30127784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01776
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