S100A4(+) Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts

S100A4, a calcium-binding protein, can promote pulmonary fibrosis via fibroblast activation. Due partly to its various cellular origins, the exact role of S100A4 in the development of lung fibrosis remains elusive. Here, we show that in the bronchoalveolar lavage fluid, numbers of S100A4(+) macropha...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Li, Yanan, Bao, Jing, Bian, Yangyang, Erben, Ulrike, Wang, Peigang, Song, Kun, Liu, Shuangqing, Li, Zhenzhen, Gao, Zhancheng, Qin, Zhihai
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088238/
https://ncbi.nlm.nih.gov/pubmed/30127784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01776
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