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Carbonic anhydrase IX is a critical determinant of pulmonary microvascular endothelial cell pH regulation and angiogenesis during acidosis

Carbonic anhydrase IX (CA IX) is highly expressed in rapidly proliferating and highly glycolytic cells, where it serves to enhance acid-regulatory capacity. Pulmonary microvascular endothelial cells (PMVECs) actively utilize aerobic glycolysis and acidify media, whereas pulmonary arterial endothelia...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Lee, Ji Young, Alexeyev, Mikhail, Kozhukhar, Natalya, Pastukh, Viktoriya, White, Roderica, Stevens, Troy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087897/
https://ncbi.nlm.nih.gov/pubmed/29631360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00446.2017
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