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Rag1-null Dahl SS rats reveal that adaptive immune mechanisms exacerbate high protein-induced hypertension and renal injury
The present study, performed in Dahl salt-sensitive (SS) and SS-Rag1(−/−) rats lacking T and B lymphocytes, tested the hypothesis that immune cells amplify salt-sensitive hypertension and kidney damage in response to a high-protein diet. After being weaned, SS and SS-Rag1(−/−) rats were placed on an...
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| Udgivet i: | Am J Physiol Regul Integr Comp Physiol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087888/ https://ncbi.nlm.nih.gov/pubmed/29537860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00201.2017 |
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