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Rag1-null Dahl SS rats reveal that adaptive immune mechanisms exacerbate high protein-induced hypertension and renal injury

The present study, performed in Dahl salt-sensitive (SS) and SS-Rag1(−/−) rats lacking T and B lymphocytes, tested the hypothesis that immune cells amplify salt-sensitive hypertension and kidney damage in response to a high-protein diet. After being weaned, SS and SS-Rag1(−/−) rats were placed on an...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Abais-Battad, Justine M., Lund, Hayley, Fehrenbach, Daniel J., Dasinger, John Henry, Mattson, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087888/
https://ncbi.nlm.nih.gov/pubmed/29537860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00201.2017
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