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Subclinical kidney injury induced by repeated cisplatin administration results in progressive chronic kidney disease
Cisplatin is used to treat many solid cancers, but its dose-limiting side effect is nephrotoxicity, causing acute kidney injury in 30% of patients. Previously, we have developed a mouse model that better recapitulates the cisplatin dosing regimen humans receive and found that repeated dosing of cisp...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087791/ https://ncbi.nlm.nih.gov/pubmed/29384415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00636.2017 |
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