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Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases

Microglia are activated after neuronal injury and in neurodegenerative diseases, and trigger neuroinflammation in the central nervous system (CNS). Microglia-derived neuroinflammation has both beneficial and detrimental effects on neurons. Because the timing and magnitude of microglial activation is...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Konishi, Hiroyuki, Kiyama, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087757/
https://ncbi.nlm.nih.gov/pubmed/30127720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00206
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