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The Double-Edged Sword of Notch Signaling in Cancer

Recent deep sequencing of cancer genomes has produced an explosion of new data implicating Notch signaling in several human cancers. Unlike most other pathways, these data indicate that Notch signaling can be either oncogenic or tumor suppressive, depending on the cellular context. In some instances...

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Detalhes bibliográficos
Main Authors: South, Andrew P., Cho, Raymond J., Aster, Jon C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360804/
https://ncbi.nlm.nih.gov/pubmed/22309843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.01.017
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