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The Double-Edged Sword of Notch Signaling in Cancer

Recent deep sequencing of cancer genomes has produced an explosion of new data implicating Notch signaling in several human cancers. Unlike most other pathways, these data indicate that Notch signaling can be either oncogenic or tumor suppressive, depending on the cellular context. In some instances...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: South, Andrew P., Cho, Raymond J., Aster, Jon C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360804/
https://ncbi.nlm.nih.gov/pubmed/22309843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.01.017
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