Notch3 inhibits epithelial–mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression

Notch3 and GATA binding protein 3 (GATA-3) have been, individually, shown to maintain luminal phenotype and inhibit epithelial–mesenchymal transition (EMT) in breast cancers. In the present study, we report that Notch3 expression positively correlates with that of GATA-3, and both are associated wit...

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Udgivet i:Oncogenesis
Main Authors: Lin, Hao-Yu, Liang, Yuan-Ke, Dou, Xiao-Wei, Chen, Chun-Fa, Wei, Xiao-Long, Zeng, De, Bai, Jing-Wen, Guo, Yu-Xian, Lin, Fang-Fang, Huang, Wen-He, Du, Cai-Wen, Li, Yao-Chen, Chen, Min, Zhang, Guo-Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087713/
https://ncbi.nlm.nih.gov/pubmed/30100605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0069-z
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