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Cancer: From Wild-Type to Mutant Huntingtin
Huntingtin (HTT) is a scaffold protein mostly known because it gives rise to the severe and incurable inherited neurological disorder Huntington’s disease (HD) when mutated. The Huntingtin gene (HTT) carries a polymorphic trinucleotide expansion of CAGs in exon 1 that ranges from 9 to 35 in the non-...
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| 發表在: | J Huntingtons Dis |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
IOS Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087435/ https://ncbi.nlm.nih.gov/pubmed/29889077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180290 |
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