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Cancer: From Wild-Type to Mutant Huntingtin

Huntingtin (HTT) is a scaffold protein mostly known because it gives rise to the severe and incurable inherited neurological disorder Huntington’s disease (HD) when mutated. The Huntingtin gene (HTT) carries a polymorphic trinucleotide expansion of CAGs in exon 1 that ranges from 9 to 35 in the non-...

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Bibliografske podrobnosti
izdano v:J Huntingtons Dis
Main Authors: Thion, Morgane Sonia, Humbert, Sandrine
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087435/
https://ncbi.nlm.nih.gov/pubmed/29889077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180290
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