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Denoising the Denoisers: an independent evaluation of microbiome sequence error-correction approaches

High-depth sequencing of universal marker genes such as the 16S rRNA gene is a common strategy to profile microbial communities. Traditionally, sequence reads are clustered into operational taxonomic units (OTUs) at a defined identity threshold to avoid sequencing errors generating spurious taxonomi...

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Vydáno v:PeerJ
Hlavní autoři: Nearing, Jacob T., Douglas, Gavin M., Comeau, André M., Langille, Morgan G.I.
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087418/
https://ncbi.nlm.nih.gov/pubmed/30123705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5364
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