Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis

BACKGROUND: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) for which several new treatment options were recently introduced. Among them is the monoclonal anti-CD52 antibody alemtuzumab that depletes mainly B cells and T cells in the immune periphery. Cons...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Simon, Micha, Ipek, Rojda, Homola, György A., Rovituso, Damiano M., Schampel, Andrea, Kleinschnitz, Christoph, Kuerten, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086993/
https://ncbi.nlm.nih.gov/pubmed/30098594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1263-9
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