CEACAM1 mediates B cell aggregation in central nervous system autoimmunity

B cell aggregates in the central nervous system (CNS) have been associated with rapid disease progression in patients with multiple sclerosis (MS). Here we demonstrate a key role of carcinoembryogenic antigen-related cell adhesion molecule1 (CEACAM1) in B cell aggregate formation in MS patients and...

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Publicat a:Sci Rep
Autors principals: Rovituso, Damiano M., Scheffler, Laura, Wunsch, Marie, Kleinschnitz, Christoph, Dörck, Sebastian, Ulzheimer, Jochen, Bayas, Antonios, Steinman, Lawrence, Ergün, Süleyman, Kuerten, Stefanie
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951702/
https://ncbi.nlm.nih.gov/pubmed/27435215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29847
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