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Activating the pregnane X receptor by imperatorin attenuates dextran sulphate sodium‐induced colitis in mice
BACKGROUND AND PURPOSE: Activation of the human pregnane X receptor (PXR; NR1I2) has potential therapeutic uses for inflammatory bowel disease (IBD). Imperatorin (IMP), a naturally occurring coumarin, is the main bioactive ingredient of Angelica dahurica Radix, which is regularly used to treat the c...
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| 出版年: | Br J Pharmacol |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086988/ https://ncbi.nlm.nih.gov/pubmed/29945292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14424 |
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