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Direct visualization of the conformational dynamics of single influenza hemagglutinin trimers
Influenza hemagglutinin (HA) is the canonical type-I viral envelope glycoprotein, and provides a template for the membrane fusion mechanisms of numerous viruses. The current model of HA-mediated membrane fusion describes a static “spring-loaded” fusion domain (HA2) at neutral pH. Acidic pH triggers...
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| Publicat a: | Cell |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086748/ https://ncbi.nlm.nih.gov/pubmed/29961575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.050 |
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