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Long-Term Administration of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND AND OBJECTIVES: In the 3-year Tolvaptan Efficacy and Safety in Management of ADPKD and Its Outcomes (TEMPO) 3:4 and 1-year Replicating Evidence of Preserved Renal Function: an Investigation of Tolvaptan Safety and Efficacy in ADPKD (REPRISE) trials, tolvaptan slowed the decline of eGFR in...

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Pubblicato in:Clin J Am Soc Nephrol
Autori principali: Edwards, Marie E., Chebib, Fouad T., Irazabal, Maria V., Ofstie, Troy G., Bungum, Lisa A., Metzger, Andrew J., Senum, Sarah R., Hogan, Marie C., El-Zoghby, Ziad M., Kline, Timothy L., Harris, Peter C., Czerwiec, Frank S., Torres, Vicente E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086720/
https://ncbi.nlm.nih.gov/pubmed/30026287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.01520218
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