Clinical Pharmacokinetics in Kidney Disease: Application to Rational Design of Dosing Regimens

A change in pharmacokinetics can alter drug exposure and predispose the patient to either over- or underdosing, potentially resulting in adverse drug reactions or therapeutic failure. Kidney disease is characterized by multiple physiologic effects, which induce clinically significant changes in phar...

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Bibliographic Details
Published in:Clin J Am Soc Nephrol
Main Authors: Roberts, Darren M., Sevastos, Jacob, Carland, Jane E., Stocker, Sophie L., Lea-Henry, Tom N.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2018
Subjects:
Nephropharmacology for the Clinician
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086693/
https://ncbi.nlm.nih.gov/pubmed/30042221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05150418
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