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Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells
The failure to develop effective therapies for paediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to quantitatively map assess the extent to which this was present in these tumours through subclonal genomic analyses, a...
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| Опубликовано в: : | Nat Med |
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6086334/ https://ncbi.nlm.nih.gov/pubmed/29967352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0086-7 |
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