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miREM: an expectation-maximization approach for prioritizing miRNAs associated with gene-set

BACKGROUND: The knowledge of miRNAs regulating the expression of sets of mRNAs has led to novel insights into numerous and diverse cellular mechanisms. While a single miRNA may regulate many genes, one gene can be regulated by multiple miRNAs, presenting a complex relationship to model for accurate...

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Foilsithe in:BMC Bioinformatics
Main Authors: Abdul Hadi, Luqman Hakim, Xuan Lin, Quy Xiao, Minh, Tri Tran, Loh, Marie, Ng, Hong Kiat, Salim, Agus, Soong, Richie, Benoukraf, Touati
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086043/
https://ncbi.nlm.nih.gov/pubmed/30097004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2292-1
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