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Determining the structural and energetic basis of allostery in a de novo designed metalloprotein assembly
Despite significant progress in protein design, the construction of protein assemblies that display complex functions (e.g., catalysis or allostery) remains a significant challenge. We recently reported the de novo construction of an allosteric supramolecular protein assembly (Zn-(C38/C81/C96)R1(4))...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6085756/ https://ncbi.nlm.nih.gov/pubmed/29996654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05812 |
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