In-Silico Characterization and in-Vivo Validation of Albiziasaponin-A, Iso-Orientin, and Salvadorin Using a Rat Model of Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, excessive acetylcholinesterase (AChE) activity, formation of neurotoxic amyloid plaque, and tau protein aggregation. Based on literature survey, we have shortlisted three important target proteins (AChE, COX2, a...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Rasool, Mahmood, Malik, Arif, Waquar, Sulayman, Tul-Ain, Qura, Jafar, Tassadaq H., Rasool, Rabia, Kalsoom, Aasia, Ghafoor, Muhammad A., Sehgal, Sheikh A., Gauthaman, Kalamegam, Naseer, Muhammad I., Al-Qahtani, Mohammed H., Pushparaj, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085546/
https://ncbi.nlm.nih.gov/pubmed/30123124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00730
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