In-Silico Characterization and in-Vivo Validation of Albiziasaponin-A, Iso-Orientin, and Salvadorin Using a Rat Model of Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, excessive acetylcholinesterase (AChE) activity, formation of neurotoxic amyloid plaque, and tau protein aggregation. Based on literature survey, we have shortlisted three important target proteins (AChE, COX2, a...

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Udgivet i:Front Pharmacol
Main Authors: Rasool, Mahmood, Malik, Arif, Waquar, Sulayman, Tul-Ain, Qura, Jafar, Tassadaq H., Rasool, Rabia, Kalsoom, Aasia, Ghafoor, Muhammad A., Sehgal, Sheikh A., Gauthaman, Kalamegam, Naseer, Muhammad I., Al-Qahtani, Mohammed H., Pushparaj, Peter N.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085546/
https://ncbi.nlm.nih.gov/pubmed/30123124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00730
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