In-Silico Characterization and in-Vivo Validation of Albiziasaponin-A, Iso-Orientin, and Salvadorin Using a Rat Model of Alzheimer's Disease

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, excessive acetylcholinesterase (AChE) activity, formation of neurotoxic amyloid plaque, and tau protein aggregation. Based on literature survey, we have shortlisted three important target proteins (AChE, COX2, a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Rasool, Mahmood, Malik, Arif, Waquar, Sulayman, Tul-Ain, Qura, Jafar, Tassadaq H., Rasool, Rabia, Kalsoom, Aasia, Ghafoor, Muhammad A., Sehgal, Sheikh A., Gauthaman, Kalamegam, Naseer, Muhammad I., Al-Qahtani, Mohammed H., Pushparaj, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085546/
https://ncbi.nlm.nih.gov/pubmed/30123124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00730
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