The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

An endogenous molecular clockwork drives various cellular pathways including metabolism and the cell cycle. Its dysregulation is able to prompt pathological phenotypes including cancer. Besides dramatic metabolic alterations, cancer cells display severe changes in the clock phenotype with likely con...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Fuhr, Luise, El-Athman, Rukeia, Scrima, Rosella, Cela, Olga, Carbone, Annalucia, Knoop, Henning, Li, Yin, Hoffmann, Karen, Laukkanen, Mikko O., Corcione, Francesco, Steuer, Ralf, Meyer, Thomas F., Mazzoccoli, Gianluigi, Capitanio, Nazzareno, Relógio, Angela
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085544/
https://ncbi.nlm.nih.gov/pubmed/30005951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.07.002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky