The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

An endogenous molecular clockwork drives various cellular pathways including metabolism and the cell cycle. Its dysregulation is able to prompt pathological phenotypes including cancer. Besides dramatic metabolic alterations, cancer cells display severe changes in the clock phenotype with likely con...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:EBioMedicine
Κύριοι συγγραφείς: Fuhr, Luise, El-Athman, Rukeia, Scrima, Rosella, Cela, Olga, Carbone, Annalucia, Knoop, Henning, Li, Yin, Hoffmann, Karen, Laukkanen, Mikko O., Corcione, Francesco, Steuer, Ralf, Meyer, Thomas F., Mazzoccoli, Gianluigi, Capitanio, Nazzareno, Relógio, Angela
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier 2018
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085544/
https://ncbi.nlm.nih.gov/pubmed/30005951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.07.002
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