NAD-Glycohydrolase Depletes Intracellular NAD(+) and Inhibits Acidification of Autophagosomes to Enhance Multiplication of Group A Streptococcus in Endothelial Cells

Group A Streptococcus (GAS) is a human pathogen causing a wide spectrum of diseases, from mild pharyngitis to life-threatening necrotizing fasciitis. GAS has been shown to evade host immune killing by invading host cells. However, how GAS resists intracellular killing by endothelial cells is still u...

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Vydáno v:Front Microbiol
Hlavní autoři: Hsieh, Cheng-Lu, Huang, Hsuan-Min, Hsieh, Shu-Ying, Zheng, Po-Xing, Lin, Yee-Shin, Chiang-Ni, Chuan, Tsai, Pei-Jane, Wang, Shu-Ying, Liu, Ching-Chuan, Wu, Jiunn-Jong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085451/
https://ncbi.nlm.nih.gov/pubmed/30123194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01733
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