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NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.

A global increase in invasive infections due to group A Streptococcus (S. pyogenes or GAS) has been observed since the 1980s, associated with emergence of a clonal group of strains of the M1T1 serotype. Among other virulence attributes, the M1T1 clone secretes NAD+-glycohydrolase (NADase). When GAS...

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Hlavní autoři: Onkar Sharma, Maghnus O'Seaghdha, Jorge J Velarde, Michael R Wessels
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-03-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC4777570?pdf=render
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