The infiltration kinetics of simian immunodeficiency virus-specific T cells drawn to sites of high antigenic stimulation determines local in vivo viral escape

Despite vigorous cell-mediated immune responses to human and simian immunodeficiency viruses (HIV/SIV) the immune system is unable to clear latently infected resting T cells. These infected cells are reactivated by antigenic stimulation, leading to viral replication. By using the SIV/macaque model o...

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Detalhes bibliográficos
Main Authors: Blancou, Philippe, Chenciner, Nicole, Cumont, Marie-Christine, Wain-Hobson, Simon, Hurtrel, Bruno, Cheynier, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60854/
https://ncbi.nlm.nih.gov/pubmed/11687626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231348598
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