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Increased glutamine anabolism sensitizes non-small cell lung cancer to gefitinib treatment
To better understand the resistance mechanism of non-small cell lung cancers (NSCLCs) to gefitinib, the metabolic profiles of gefitinib-resistant A549 cells and gefitinib-sensitive PC-9 cells were analyzed with a metabolomics analytical platform. A549 and PC-9 cells exhibited significant differences...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6085389/ https://ncbi.nlm.nih.gov/pubmed/30109143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0086-x |
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